A concert pianist since the age on nine, Luis Magalhães has given numerous recital, concerto and chamber music performances in Europe, Asia, South America and Africa, eliciting rave reviews. His teachers have included Eduardo Rocha, José Alexandre Reis, Pedro Burmester and Vladimir Viardo, and he has received master classes from such noted performers as Helena Sá e Costa, Paul Badura-Skoda and Alicia de Larrocha.

Magalhães has won several prizes at national and international level, including first prize at the Maria Campina Competition, second prize at the Juventude Musical Portuguesa Competition, second prize for chamber music at the Jóvens Músicos Competition, honorary mention at the Helena Sá e Costa Competition, as well as second prize for the best performance of Russian music and first prize for the best performance of Rachmaninoff at the 2002 Russian Music International Piano Competition.

Together with his wife, pianist Nina Schumann, Magalhães has formed the TwoPianists Piano Duo - widely regarded as one of the top piano duos in the world today. Their performances have been met with overwhelming critical praise, while their recordings of the complete works for two pianos by Rachmaninoff, and works by Brahms, Arensky, Lutoslawski and Copland, have received rave reviews from such publications as the American Record Guide, International Record Review, Fanfare and Piano News. Their third recording, Bach's Goldberg Variations (in the arrangement for two pianos by Rheinberger/Reger), was released in 2013, while 2015 sees the much-anticipated release of their recording of works for two pianos by American composers.

In addition to his piano duo recordings, Magalhães' discography includes a ground-breaking version of the Beethoven Cello Sonatas with cellist Peter Martens, named Best Classical Recording at the 2011 South African Music Awards, and a recital of works by Janáček, Schumann and Schubert with violinist Frank Stadler. Three of his CD's have been shortlisted for Grammy nominations.

Magalhães is co-founder and director of TwoPianists Records, a leading classical music record label known for the unwavering commitment to sound quality and artistic integrity of its releases of recordings by leading international artists such as mezzo soprano Michelle Breedt, pianists Konstantin Scherbakov, Lukáš Vondrácek and Lori Sims, violinists Daniel Rowland and Frank Stadler, and conductor Daniel Raiskin.

Aside from his teaching duties as Piano Professor at the Department of Music, University of Stellenbosch, Magalhães is closely involved in the management of projects such as the Stellenbosch International Chamber Music Festival and the biannual Stellenbosch International Piano Symposium.

In May 2014 Luis Magalhães became Yamaha International Artist.